MAG Technique Shows Promise for Gastric Cancer

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Results

The MAG-ESD technique was utilized in 25 patients. All tumors were resected en bloc (median size 5.5 cm), without any perforations or uncontrollable bleeding. All magnetic anchors were safely removed.

The MAG system was evaluated as helpful in facilitation ESD in 23 of the 25 patients. In 21 patients, only one magnetic anchor was needed to achieve the desired result, either by rotating the patient or by moving the examination table. The MAG system effectively facilitated an ESD for all nine tumors located on the greater curvature of the gastric body.

None of the patients experienced physiological or mental abnormalities as a result of magnetic field exposure either during the procedure itself or over the follow-up interval. No delayed adverse effects or allergies were observed because of the stainless steel of the magnetic anchor. Eight weeks after an MAG-ESD, all artificial defects caused by ESD were completely healed. Neither recurrent cancer nor distant metastases were observed in any of the patients during follow-up.

The study authors noted that the electromagnetic control system was cumbersome and advised that the system should be miniaturized to allow wider clinical application. While this human clinical trial demonstrated MAG-ESD’s feasibility and safety, and offered excellent visualization due to suitable tissue tension, the researchers advised that further innovations are warranted to apply the MAG procedure in daily clinical practice.

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