PHILADELPHIA—Postmenopausal women who were overweight or obese and lost at least 5 percent of their body weight had a measurable reduction in markers of inflammation, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.
“Both obesity and inflammation have been shown to be related to several types of cancer, and this study shows that if you reduce weight, you can reduce inflammation as well," said Anne McTiernan, MD, PhD, director of the Prevention Center at the Fred Hutchinson Cancer Research Center in Seattle.
Women in the trial who were assigned to a weight-loss intervention had a goal of 10 percent weight reduction during the course of one year achieved through a diet intervention with or without aerobic exercise.
“So this program was highly achievable and reproducible. We are not talking about drastic weight loss," said McTiernan.
The researchers measured levels of C-reactive protein, serum amyloid A, interleukin-6, leukocyte and neutrophil in 439 women.